I-Cryptococcosis Emakati - Izimpawu kanye Nokwelapha

Umlobi: Laura McKinney
Usuku Lokudalwa: 3 Epreli 2021
Ukuvuselela Usuku: 19 Unovemba 2024
Anonim
I-Cryptococcosis Emakati - Izimpawu kanye Nokwelapha - Izifufuzo Ezifuywayo
I-Cryptococcosis Emakati - Izimpawu kanye Nokwelapha - Izifufuzo Ezifuywayo

-Delile

I-Feline cryptococcosis yiyona isifo se-systemic esibangelwa isikhunta okuvame kakhulu emakati, noma kunjalo, izehlakalo zayo kubantu besibalo ziphansi. I-Cryptococcosis yenzeka kakhulu esifundeni samakhala, iveze i-edema kwesinye isikhathi engabonakala kakhulu ngenxa yokuthuthukiswa kwe-fungal granuloma. Ngezinye izikhathi, i-cryptococcosis ithinta amaphaphu, amehlo, uhlelo lwezinzwa noma ifomu elinohlelo, lapho kwenzeka ezindaweni ezahlukahlukene zomzimba lapho isatshalaliswa ngomzila we-hematogenous noma we-lymphatic. Ukwelashwa kusekelwe ekusetshenzisweni kokwelapha okwenzelwe ukubulala imvubelo futhi, kwesinye isikhathi, ukwenziwa kabusha kwe-fungal granuloma ekati nakho kungenziwa.


Kule ndatshana yePeritoAnimal, sizokhuluma ngayo i-cryptococcosis emakati, izimpawu zayo kanye nokwelashwa, ukuze ukwazi ukuqonda kangcono lesi sifo esivame kakhulu futhi ufunde ukusibona.

yini i-feline cryptococcosis

I-Feline cryptococcosis yisifo esithathelwanayo esithinta amakati futhi sibangelwa isikhunta. Ngokuqondile, umenzeli wefungal ovame ukuhlukaniswa kakhulu yi- I-Cryptococcus neoformans, ukuba yisifo esihambisana nezindawo zokuhlala lapho kunezinyoni, ikakhulukazi amajuba, ngoba zitholakala endleni yazo. Kungabangelwa futhi yi- Cryptococcus gattii, imvamisa ezindaweni ezisezindaweni ezishisayo noma ezishisayo, futhi umthombo wokutheleleka udaba lwezihlahla ezithile.

Kuyimvubelo encane esatshalaliswa emhlabeni wonke. Ine-capsule okuthi, ngaphezu kokuyivikela ekomeni, yenze kube nzima kumasosha omzimba ekati ukuyibona ukuze ibangele ukusabela kwamasosha omzimba okudingekayo ukuze kuqedwe. Noma kunjalo, yisifo sezigameko eziphansi.


Isici sengcuphe sokuthuthukiswa kwe-cryptococcosis emakati abangelwa yi- C. ama-neoformans kuba khona kwezifo zokuzivikela ezifweni ezifana ne-feline leukemia noma i-feline immunodeficiency. Noma kunjalo, ukutheleleka nge C. gattii kungenzeka kubantu abangenalo uhlelo lokuzivikela lomzimba olubekiwe. Kodwa-ke, kubantu abangenakuyekethisa ukutheleleka kuvame ukuba nzima kakhulu, kanti kubantu abanamasosha omzimba aqinile, ukutheleleka kuvame ukwenziwa esifundeni. ngamakhala, ngaphandle kokusabalala.

Injani i-pathogenesis ye-cryptococcosis?

Umthombo oyinhloko wokutheleleka kwe-cryptococcosis emakati wenziwa ukuhogela imvubelo, ezibekwa ezindleleni zomoya ezingenhla, lapho zikhiqiza khona ama-granulomas acinene. Uma befika ezindleleni zomoya ezingezansi zamaphaphu, babangela ama-granulomas ephashini.


O ukhunta ungasakazekela nakwezinye izindawo, njengesistimu yezinzwa emaphakathi, ngegazi, i-lymphatic noma ukuhlasela kwendawo ngokusebenzisa ungqimba lwe-cribriform lwethambo le-ethmoid, elixhumanisa ubuchopho nomgodi wamakhala. Bangakwazi futhi ukufinyelela kwezinye izindawo njengamehlo, ubuso nesikhumba. Uma kwenzeka isimo esibi sesifo, imvubelo ingasakazeka ezithweni ezinjengobende, inhliziyo, izinso, izitho zokugaya ukudla, imisipha noma ama-lymph node.

Izimpawu ze-cryptococcosis emakati

I-Cryptococcosis ingadala izimpawu zomtholampilo ezihluke kakhulu ngokuya ngendawo yemvubelo nezinga lokusatshalaliswa kwalo. Kungaba nezinhlobo eziningana ze-cryptococcosis emakati: ekhaleni, emaphashini, enovalo, e-ocular nase-systemic.

i-cryptococcosis yamakhala

Ku-nasal cryptococcosis emakati, izimpawu ezivame kakhulu ukuphefumula, nge izimpawu zomgudu wokuphefumula ezingenhla:

  • Ukuphuma komlomo noma kwegazi noma ukuphuma kwamabili.
  • I-Rhinitis.
  • Ukuvuvukala kwamakhala.
  • AmaGranulomas.
  • Ukuthimula.
  • Imigwaqo yokuphefumula.
  • Ache.
  • Ubunzima bokuphefumula.

I-cryptococcosis yamaphaphu

Lolu hlobo lwe-cryptococcosis emakati lwenzeka lapho imvubelo ithinta amaphaphu kanye nama-granulomas, i-pneumonia foci, nokungena ngaphakathi kwe-bronchi. izimpawu eziphansi zomoya, njengo:

  • Khwehlela.
  • Ubunzima bokuphefumula.
  • Imfiva.
  • Imisindo yamaphaphu.

I-cryptococcosis yezinzwa

I-Cryptococcosis nayo ingathinta uhlelo lwezinzwa, lapho lungabonakala khona. izimpawuuvalo okungaba umphumela we-encephalitis noma i-meningitis ngenxa yokuba khona kwemvubelo ohlelweni lwezinzwa oluphakathi, njenge:

  • Ukudilizwa kwabafundi (i-mydriasis).
  • Ukushintsha kwamagiya.
  • Ukungavumelani.
  • Ukunganaki.
  • Ukungaboni okuphelele noma okuyingxenye.

i-cryptococcosis eyindilinga

Lapho imvubelo ingena esweni, kwenzeka lezi zimpawu ezilandelayo:

  • I-optic neuritis.
  • I-Chorioretinitis.
  • I-Mydriasis.

i-cryptococcosis ehlelekile

Lapho i-cryptococcosis ithinta izifunda ezahlukahlukene zomzimba wekati, a izimpawu ezahlukahlukene kungenzeka, lokhu kube yisifo esibi kakhulu kulesi sifo. Phakathi kwalezi zimpawu, okulandelayo kuyabonakala:

  • Imfiva.
  • Khwehlela.
  • Ukuncipha kwepulmonary.
  • I-Anorexia.
  • Ukwehla kwesisindo.
  • Ubuthakathaka.
  • I-Ataxia.
  • Izilonda ze-mucosal.
  • Kunzima ukuhamba.
  • Ukuhlanza.
  • Uhudo.
  • Ama-granulomas ahlukanisiwe.
  • Ama-lymph node akhulisiwe.

Ukuxilongwa kwe-cryptococcosis emakati

Ukuxilongwa kwenziwa ngokucatshangelwa, ngaphezu kwezimpawu zomtholampilo nomlando wokwelashwa kwesilwane, ilabhoratri nezivivinyo ezihambisanayo, kufaka phakathi ukuhlukaniswa nokuhlonza i-microorganism yi-cytology namasiko, kanye nokunqunywa kwe-yeast capsule antigen. Lezi zivivinyo zilandelayo:

  • THE cytology yenziwa ngokubhoboza izindawo ezithintekile, ezinjenge-lymph node, izixuku esifundeni samakhala noma esikhunjeni. Ngemuva kwalokho, kuyabonakala ngaphansi kwesibonakhulu esinombala, njenge-Gram, i-methylene eluhlaza okwesibhakabhaka, i-Wright neyinki yaseChina, ukubona ngeso lengqondo umzimba. Kuyinto elula ukuthola kalula ngenxa yesici sayo se-polysaccharide capsule.
  • THE isiko yenziwa kusuka kumasampula we-cerebrospinal fluid noma ama-exudates. Amasampula kufanele afakwe ku-Sabouraud agar noma i-agar yegazi ezingeni lokushisa eliphakathi kuka-25 no-35 ºC. Ngemuva kwamahora angama-36-72, uma kuvela amakholoni amahle, akhanyayo amhlophe qwa. amakoloni we C. ama-neoformans amafinyila amancane kunalawo we C. gattii. Ukuthola imvubelo, kubalulekile ukubona ngeso lengqondo i-capsule bese uqinisekisa izici zayo zamakhemikhali, njengamandla ayo okunciphisa ama-nitrate kuma-nitrites kanye ne-hydrolyze urea.
  • Ukuthola i-capsule antigen, i- ukuhlolwa kwe-latex agglutination, noma i-ELISA, yenziwa ngamasampuli we-serum yegazi, i-cerebrospinal fluid noma umchamo. Lokhu kuhlolwa kunokuzwela okuphezulu kanye nokucaciswa kwekati.

I-radiography yesifuba ingasiza ekuboneni ngamehlo ushintsho lwe-pulmonary kanye ne-bronchial esimweni se-pulmonary cryptococcosis.

Ukwelashwa kwe-feline cryptococcosis

Iphrothokholi yokwelapha ye-cryptococcosis emakati ihlanganisa ukwelashwa nge i-antifungal ukubulala imvubelo nokuhlinzwa kabusha kwama-granulomas. THE ukuhlinzwa okuhlinzekwayo wenziwa emakati anama-granulomas emgodini wamakhala njengokuhambisana nokwelashwa ngama-antifungal agents.

Ama-antifungal asetshenziswa kakhulu ekwelapheni i-cryptococcosis emakati yilawa:

  • I-Fluconazole: ngumuthi ovikela uketshezi ovame kakhulu namuhla ngoba yiyona ephumelela kunazo zonke futhi ephephe kunazo zonke. Umthamo wamahora angama-50 mg / 12 usetshenziswa ngomlomo. Kuyasebenza futhi ekwelapheni izifo zemizwa ngokuwela umgoqo wegazi nobuchopho.
  • itraconazole: i-itraconazole yamakati nayo iyasebenza njenge-fluconazole, kepha ingaba nobuthi esibindini, ngakho-ke, ifuna ukunakekelwa kudokotela wayo.
  • Ketoconazole: Iyasebenza kepha ayisebenziseki ku-cryptococcosis nervosa, futhi ingadala imiphumela emibi njengokuhlanza nokulahlekelwa isifiso sokudla emakati.
  • I-Amphotericin B ene-5-fluorocytosine: kuyindlela yokwelashwa ewusizo kakhulu lapho kunezimpawu zokwethuka. Kusetshenziswe kakhulu eminyakeni embalwa edlule.

Kunoma ikuphi, kubalulekile ukuya emtholampilo wezilwane ukuze uchwepheshe aqinisekise lesi sifo futhi athole ukwelashwa okuhle kakhulu. Akufanele neze uzenzele ikati umuthi wedwa.

Manje njengoba usukwazi konke mayelana ne- i-cryptococcosis emakati, sikumema ukuba uzazise ngevidiyo elandelayo mayelana nezifo ezivame kakhulu phakathi kwamakati:

Lo mbhalo wenzelwe imininingwane kuphela, kwaPeritoAnimal.com.br asikwazi ukunquma ukwelashwa kwezilwane noma ukwenza noma yiluphi uhlobo lokuxilongwa. Siphakamisa ukuthi uthathe isilwane sakho uye kudokotela wezilwane uma kungenzeka ukuthi unanoma yiluphi uhlobo lwesimo noma ukungaphatheki kahle.

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