-Delile
- Yini futhi yini ebanga ukuvuvukala kwamathumbu emakati?
- Ngabe kukhona ubuhlanga noma iminyaka yobudala ekukhuleni kwe-feline IBD?
- Izimpawu Zesifo Samathumbu Esivuthayo Emakati
- Ukuxilongwa Kwesifo Samathumbu Esivuthayo Emakati
- Ukwelashwa Kwezifo Zokuvuvukala Kwamathumbu Emakati
- ukwelashwa kokudla
- Ukwelashwa
Ukuvuvukala kwamathumbu noma IBD emakati iqukethe ukuqoqwa kwamaseli wokuvuvukala kumucosa wamathumbu. Lokhu kunqwabelana kungaba ama-lymphocyte, amaseli e-plasma noma ama-eosinophil. Emakati, kwesinye isikhathi kuhambisana nokuvuvukala kwamanyikwe kanye / noma isibindi, ngakho-ke kuthiwa yi-feline triad. Izimpawu zomtholampilo yizimpawu ezijwayelekile zenkinga yokugaya ukudla, yize ukuhlanza nokuncipha kwesisindo kwenzeka kaningi, ngokungafani nohudo olungapheli oluvame ukwenzeka ezinjeni.
Ukuxilongwa kokuhlukaniswa okuhle kufanele kwenziwe phakathi kwezinye izifo ezikhiqiza izimpawu ezifanayo, futhi ukuxilongwa okucacile kutholakala nge-histopathology. O ukwelashwa kuzoba ngokudla okuthile okuhlangene nokusetshenziswa kwemithi.
Qhubeka ufunde le ndatshana yePeritoAnimal, lapho sizochaza khona okudingeka ukwazi ngakho Isifo Samathumbu Esivuthayo Emakati - Izimpawu kanye Nokwelapha.
Yini futhi yini ebanga ukuvuvukala kwamathumbu emakati?
Isifo samathumbu esivuthayo emakati noma i-IBD yi- Isifo esingelapheki sokuvuvukala kwamathumbu amancane esingaziwa ngemvelaphi yaso. Ngesinye isikhathi, ingafaka futhi amathumbu amakhulu noma isisu futhi ihlotshaniswe ne-pancreatitis kanye / noma i-cholangitis, ebizwa ngokuthi yi-feline triad.
Esifweni sesibindi sokuvuvukala, kukhona ukungena kwamangqamuzana okuvuvukala (ama-lymphocyte, amaseli e-plasma noma ama-eosinophils) ku-lamina propria yoqweqwe lwe-mucosal lwamathumbu, olungafinyelela ezingxenyeni ezijulile. Yize imvelaphi ingaziwa, kunemicabango emithathu mayelana ne- Izimbangela Zesifo Samathumbu Esivuthayo Emakati:
- Ukuguqulwa okuzenzakalelayo ngokumelene ne-epithelium yamathumbu uqobo.
- Impendulo kuma-antigen wegciwane, ama-parasitic, noma wokudla avela ku-lumen gut.
- Ukwehluleka ukungena kwe-mucosa yamathumbu, okubangela ukuvezwa okukhulu kulawa ma-antigen.
Ngabe kukhona ubuhlanga noma iminyaka yobudala ekukhuleni kwe-feline IBD?
Akunabudala obuthile. Yize kubonakala kakhulu emakati aneminyaka ephakathi nendawo, amakati amancane namadala nawo angathinteka. Ngakolunye uhlangothi, kunokuthambekela okuthile kobuhlanga emakati e-Siamese, Persian nase-Himalaya.
Izimpawu Zesifo Samathumbu Esivuthayo Emakati
Njengoba ukuvuvukala kwenzeka emathunjini, izimpawu zomtholampilo zifana kakhulu nalezo zamathumbu emathunjini, njengoba kunikezwe ukuthi, yize kuvame ukwenzeka kakhulu emakati amadala, akukhona okukhethekile. Ngakho-ke, izimpawu zomtholampilo zokuthi ikati elinezifo zezifo ezivuthayo yilezi:
- I-anorexia noma isifiso esijwayelekile.
- Ukwehla kwesisindo.
- Ukuhlanza okumunyu noma okuyisiqu.
- Uhudo oluncane.
- Uhudo olukhulu uma lokhu kuthintekile futhi, kuvamise ukuba negazi esitokisini.
Lapho senza i-palpation yesisu, singabona ukwanda kokuvumelana kwamalokhi amathumbu noma ama-lymph node akhulisiwe e-mesenteric.
Ukuxilongwa Kwesifo Samathumbu Esivuthayo Emakati
Ukuxilongwa okucacile kwe-IBE ye-feline kutholakala ngokuhlanganiswa komlando omuhle, ukuhlolwa komzimba, ukuhlaziywa kwelabhoratri, ukuxilongwa kwe-imaging kanye ne-histopathology yama-biopsies. Kuyadingeka ukwenza ifayili le- ukuhlolwa kwegazi kanye ne-biochemistry, Ukutholwa kwe-T4, ukuchama kwe-urinalysis, kanye ne-rayography yesisu ukukhipha izifo zesistimu ezifana ne-hyperthyroidism, isifo sezinso, noma ukwehluleka kwesibindi.
Kwesinye isikhathi kungabonakala i-CBC yokuvuvukala okungapheli nokwanda kwama-neutrophils, ama-monocyte nama-globulin. Uma kunokushoda kukavithamini B12, lokhu kungakhombisa ukuthi inkinga isengxenyeni yokugcina yamathumbu amancane (ileum). Ngokulandelayo, i i-radiography yesisu ingathola izidumbu zangaphandle, amagesi noma ileus ekhubazekile. Kodwa-ke, i- i-ultrasound yesisu wukuhlolwa kwe-imaging okuwusizo kakhulu, ukwazi ukubona ukuqina kodonga lwamathumbu, ikakhulukazi i-mucosa, futhi ulilinganise.
Akuvamile ezifweni ezivuthayo zamathumbu emakati ukuthi ukulahleka kwezingqimba zamathumbu kulahlekile, njengoba kungenzeka nge-tumor yamathumbu (i-lymphoma). Kungenzeka futhi ukuthi uqaphele ifayili le- ukwanda kwama-lymph node mesenteric futhi, kuya ngosayizi nokuma kwawo, ukuthi avuvukile yini noma anezicubu.
Ukuxilongwa okucacile nokuhlukile nge-lymphoma kuzotholakala nge ukuhlaziywa kwe-histopathological amasampula atholwe ngu i-endoscopic biopsy noma i-laparotomy. Ezimweni ezingaphezu kwezingu-70%, ukungena kungena nge-lymphocytic / plasmocytic, yize kungabuye kube yi-eosinophilic enempendulo ephansi ekwelashweni. Okunye ukungena ngaphakathi okungenzeki kakhulu ama-neutrophilic (neutrophils) noma i-granulomatous (macrophages).
Ukwelashwa Kwezifo Zokuvuvukala Kwamathumbu Emakati
Ukwelashwa kwesifo samathumbu esivuthayo emakati emakati kususelwa enhlanganisweni yokudla kanye nama-immunomodulators futhi, uma kukhona, ukwelashwa kwama-comorbidities.
ukwelashwa kokudla
Amakati amaningi ane-IBD angcono ezinsukwini ezimbalwa nge Ukudla kwe-hypoallergenic. Lokhu kungenxa yokuthi ukudla kunciphisa i-substrate yokukhula kwamagciwane, kukhulisa ukumuncwa kwamathumbu futhi kunciphise amandla we-osmotic. Yize ukushintsha lokhu kudla kungenza izitshalo zesisu zibe ezijwayelekile, kunzima ukunciphisa izinhlobo zezinto eziphilayo ezithinta kakhulu amathumbu. Ngaphezu kwalokho, uma kune-pancreatitis ehambisanayo, kufanele kunikezwe ama-antibiotic ukuvimbela ukutheleleka emgodleni we-bile noma emathunjini ngenxa yezimpawu zokwakheka kwekati (i-feline triad).
Uma amathumbu amakhulu nawo ethintekile, ukusetshenziswa kwe- ukudla okuphezulu kwe-fiber kungaboniswa. Kunoma ikuphi, kuzoba ngudokotela wezilwane ozokhombisa ukudla okungcono kakhulu kwamakati ane-IBD ngokususelwa ecaleni lakho elithile.
Ukwelashwa
Uma unenani eliphansi le- b12 amavithamini, ikati kufanele lilekelelwe ngomthamo wama-micrograms angama-250 ngokuzithoba kanye ngesonto amasonto ayisithupha. Ngemuva kwalokho, njalo emavikini ama-2 amanye amaviki ayisithupha bese kuba nyangazonke.
O metronidazole iyasebenza ngoba iyi-antimicrobial and immunomodulatory, kepha kufanele isetshenziswe kahle ukugwema imiphumela emibi kumaseli emathumbu kanye ne-neurotoxicity. Ngakolunye uhlangothi, basebenzisa i- ama-corticosteroids njenge-prednisolone kumithamo ye-immunosuppressive. Lokhu kwelashwa kufanele kwenziwe, noma ngabe indlela yokudla ayikashintshwa ukuze kuhlolwe i-hypersensitivity yokudla, emakati abonisa ukwehla kwesisindo nezimpawu zokugaya ukudla.
Ukwelashwa nge-prednisolone kungaqalwa nge-2 mg / kg / 24h ngomlomo. Umthamo, uma kukhona ukuthuthuka, ugcinwa kwamanye amasonto ama-2 kuye kwangu-4. Uma izimpawu zomtholampilo zincipha, umthamo wehliselwa ku-1 mg / kg / 24h. umthamo kumele yehliswe kuze kube yilapho ufinyelela umthamo ophansi kakhulu ovumela ukulawula izimpawu.
Uma ama-corticosteroids enganele, kufanele athulwe amanye ama-immunosuppressants, njengo:
- I-Chlorambucil ngomthamo ka-2 mg / ikati ngomlomo njalo ngamahora angama-48 (amakati anesisindo esingaphezu kuka-4 kg) noma njalo ngamahora angama-72 (amakati anesisindo esingaphansi kuka-4 kg). Ukubalwa kwegazi okuphelele kufanele kwenziwe njalo emavikini ama-2-4 uma kwenzeka umnkantsha we-aplasia.
- ICyclosporine ngomthamo wama-5 mg / kg / amahora angama-24.
O ukwelashwa kwesifo samathumbu esivuthayo emakati kuhlanganisa:
- Ukudla kwe-Hypoallergenic kwezinsuku ze-7 nokuhlolwa kwempendulo.
- I-Metronidazole izinsuku eziyi-10 ngomthamo we-15mg / kg / 24 amahora ngomlomo. Nciphisa umthamo ngo-25% njalo emavikini amabili kuze kube ukuhoxa.
- Uma kungekho mpendulo ngokwelashwa okungenhla, i-prednisolone 2 mg / kg / 24h kufanele iqalwe yodwa noma ihlanganiswe ne-metronidazole, ukunciphisa umthamo ngo-25% njalo emavikini amabili kuze kufinyelelwe umthamo omncane osebenzayo.
Futhi manje njengoba unezinhlobo ezahlukahlukene zokwelashwa kwamakati ezifo zesifo samathumbu emakati, ungahle ube nentshisekelo yokwazi ukuthi yiziphi izifo ezivame kakhulu emakati. Ungaphuthelwa yividiyo elandelayo:
Lo mbhalo wenzelwe imininingwane kuphela, kwaPeritoAnimal.com.br asikwazi ukunquma ukwelashwa kwezilwane noma ukwenza noma yiluphi uhlobo lokuxilongwa. Siphakamisa ukuthi uthathe isilwane sakho uye kudokotela wezilwane uma kungenzeka ukuthi unanoma yiluphi uhlobo lwesimo noma ukungaphatheki kahle.
Uma ufuna ukufunda izindatshana eziningi ezifana ne- Isifo Samathumbu Esivuthayo Emakati - Izimpawu kanye Nokwelapha, sincoma ukuthi ufake isigaba sethu sezinkinga zamathumbu.