-Delile
- Kuyini Bilirubin?
- Kungani i-jaundice ivela emakati?
- Izimpawu ze-jaundice emakati
- i-jaundice yesibindi
- Yiziphi izimbangela ezingadala i-jaundice yesibindi emakati?
- i-jaundice ye-post-hepatic
- i-jaundice engeyona i-hepatic
- Ngazi kanjani ukuthi yini ebangela i-jaundice ekati lami?
THE i-jaundice ichazwa njenge i-pigmentation ephuzi yesikhumba, umchamo, i-serum nezitho ezibangelwa ukuqongelela kwe-bilirubin, egazini nasezicutshini. Kuyisibonakaliso somtholampilo esingavela ezifweni eziningi. Uma ikati lakho linombala ongajwayelekile kunoma iyiphi ingxenye yomzimba, udokotela wezilwane kufanele enze izivivinyo ezihlukile ukuze akwazi ukuthola ukuxilongwa okwehlukile.
Uma ikati lakho lihlangabezana nalezi zinguquko futhi ungathanda ukwazi okwengeziwe ngemvelaphi yalo, funda le ndatshana ngabakwaPeritoAnimal lapho sichaza khona ngokuningiliziwe izimbangela ezivame kakhulu ze-jaundice emakati.
Kuyini Bilirubin?
I-Bilirubin ingumkhiqizo imiphumela yokucekelwa phansi kwe-erythrocyte (amangqamuzana abomvu egazi) lapho efinyelela ekupheleni kwempilo yawo (okuthatha cishe izinsuku eziyi-100). Amaseli abomvu egazi abhujiswa ebuchosheni nasemnkantsheni wethambo futhi, kusuka kumbala obanikeze umbala wabo - i-hemoglobin, kwakheka enye i-pigment, ngombala ophuzi, i-bilirubin.
Kuyinqubo eyinkimbinkimbi lapho i-hemoglobin iqala khona ngokuguqulwa ibe yi-biliverdin ephenduka ibe yi-bilirubin encibilikayo. I-Bilirubin kamuva ikhishelwa ekusakazeni, ihamba kanye neprotheyini ize ifike esibindini.
Esibindi, umshini omkhulu wokuhlanza umzimba, uguqula ube yi-bilirubin ehlanganisiwe futhi igcinwa enyameni. Njalo lapho i-gallbladder ithululela emathunjini amancane, ingxenye encane yamaqabunga e-bilirubin enezingxenye ezisele ze-bile. Ngokwenza kwamagciwane athile, i-bilirubin iguqulwa ibe yizingulube ezijwayelekile esizibonayo nsuku zonke: i-stercobilin (ifaka isitokisi) ne-urobilinogen (imibala umchamo).
Kungani i-jaundice ivela emakati?
Okwamanje mhlawumbe ukubonile lokho isibindi kuyisihluthulelo. I-jaundice ivela lapho umzimba ukhona ayikwazi ukukhipha kahle i-bilirubin nezingxenye ezisele ze-bile. Ukunquma ukuthi lokhu kwehluleka kubangelwa yini kuwumsebenzi onzima kakhulu.
Ukwenza lula lesi sihloko esiyinkimbinkimbi esingakhuluma ngaso:
- i-jaundice yesibindi (lapho imbangela isesibindi).
- i-jaundice ye-post-hepatic (isibindi senza umsebenzi waso ngendlela efanele kepha kukhona ukwehluleka ekugcineni nasekuthumeleni).
- i-jaundice engeyona i-hepatic (lapho inkinga ayihlangene neze nesibindi, noma nokugcinwa kanye nokukhishwa kwe-pigment).
Izimpawu ze-jaundice emakati
Njengoba kushiwo ekuqaleni kwalesi sihloko, i-jaundice iyisibonakaliso somtholampilo esibonisa ukuthi i-feline inenkinga ethile yezempilo. Uphawu olusobala lwale nkinga umbala ophuzi wesikhumba, obonakala kakhulu emlonyeni, endlebeni nasezindaweni ezinezinwele ezincane.
i-jaundice yesibindi
Isibindi se-jaundice senzeka lapho okuthile kwehluleka ezingeni lesibindi, okungukuthi, lapho isibindi singakwazi ukufeza umsebenzi saso futhi ayikwazi ukukhipha i-bilirubin eza kuye. Ngaphansi kwezimo ezijwayelekile, amaseli wesibindi (ama-hepatocyte) akhipha le pigment ku-bile canaliculi futhi ukusuka lapho kudlulela ku-gallbladder. Kepha lapho amaseli ethinteka yisifo esithile, noma kukhona ukuvuvukala okuvimbela ukudlula kwe-bilirubin emadokodweni e-bile, cholestasis yangaphakathi.
Yiziphi izimbangela ezingadala i-jaundice yesibindi emakati?
Noma yikuphi ukugula okuthinta ngqo isibindi kungaveza lokhu kunqwabelana kwe-bilirubin. Emakati sinakho okulandelayo:
- isibindi lipidosis: isibindi esinamafutha emakati singabonakala njengomphumela wokuzila isikhathi eside emakati akhuluphele. Amafutha adluliselwa esibindi ngomzamo wokuthola izakhamzimba, phakathi kwezinye izizathu. Kwesinye isikhathi akukwazeki ukwazi ukuthi lokhu kuhamba ngani futhi kufanele sibize inkinga nge-idiopathic hepatic lipidosis.
- isimila: ikakhulukazi ezigulini ezindala, ama-neoplasms ayisisekelo ayimbangela ejwayelekile yokuhluleka kwesibindi.
- i-feline hepatitis: ama-hepatocyte angabhujiswa yizinto ikati elizifakile ngengozi futhi ezingaholela ku-hepatitis emakati.
- ukuqina kwesibindi: i-fibrosis ye-biliary canaliculi ibangela ukungakwazi ukufeza umsebenzi wokudlulisa i-bilirubin ku-gallbladder.
- Izinguquko ezingeni le-vascular.
Kwesinye isikhathi, kunezinguquko ezingadala ukwehluleka kwesibindi ezingeni lesibili, okungukuthi, kukhiqizwa yizifo ezinemiphumela emibi esibindini. Singathola, isibonelo, izibindi ezithintwe yi- Ama-neoplasms angaphezulu kwe-feline leukemia. Singathola nezinguquko noma ukulimala kwesibindi okubangelwa i-feline peritonitis esithathelwanayo, i-toxoplasmosis noma ngenxa yesifo sikashukela. Njengomphumela wanoma iyiphi yalezi zinkinga, sizobona i-jaundice ibonakala kakhulu ekatini.
i-jaundice ye-post-hepatic
Imbangela yokuqongelelwa kwe-bilirubin ngu ngaphandle kwesibindi, lapho i-pigment isivele idlulile kuma-hepatocyte azocutshungulwa. Isibonelo, ukuvinjelwa komshini we-extrahepatic bile duct, okufaka i-bile ku-duodenum. Lokhu kuvinjelwa kungabangelwa:
- i-pancreatitis, ukuvuvukala kwamanyikwe.
- isimila ku-duodenum noma kumanyikwe, okucindezela indawo ngokusondela futhi kwenze kube nzima ukukhipha okuqukethwe yinyongo.
- ikhefu ngenxa yokuhlukumezeka emgodini we-bile, lapho i-bile ingenakudluliselwa khona emathunjini (ukugijima, ukushaya, ukuwa efasiteleni ...)
Ezimweni lapho kunokuphazamiseka okuphelele kokugeleza kwenyongo (ukuqhekeka komgudu wenyongo) singabona umbala ophuzi wezinambuzane noma isikhumba. Kungabuye kube nezitulo ezingenambala, njengoba i-pigment ebanika umbala ingafinyeleli emathunjini (stercobilin).
i-jaundice engeyona i-hepatic
Lolu hlobo lwe-jaundice emakati lwenzeka lapho inkinga i- ukukhiqizwa okweqile kwe-bilirubin, ngendlela yokuthi isibindi asikwazi ukukhipha inani elengeziwe le-pigment, yize kungekho lutho olonakele kulo, noma ekuthuthweni kwe-duodenum. Kwenzeka, isibonelo, ku i-hemolysis (ukuqhekeka kwamaseli abomvu egazi), okungahle kube ngenxa yezici ezinjenge:
- anobuthi: ngokwesibonelo, i-paracetamol, i-mothballs noma u-anyanisi yizinto ezibangela ukuwohloka kwamangqamuzana abomvu egazi aphilile, okwenza i-anemia nokugcwala ngokweqile ohlelweni oluphethe ngokucekela phansi izinsalela zala maseli egazi.
- Ukutheleleka ngegciwane noma amagciwane, njenge-hemobartonellosis. Ama-antigen abekwa ebusweni bamaseli abomvu egazi futhi amasosha omzimba awakhomba njengezinjongo zokubhujiswa. Kwesinye isikhathi, alukho usizo lwangaphandle oludingekayo, futhi amasosha omzimba ngokwawo ahluleka futhi aqale ukushabalalisa amaseli awo abomvu ngaphandle kwesizathu.
- i-hyperthyroidism: indlela i-jaundice ekhiqizwa ngayo emakati anamakati ane-hyperthyroidism ayaziwa kahle, kepha kungenzeka kungenxa yokwehla kokonakala kwamaseli abomvu egazi.
Ngazi kanjani ukuthi yini ebangela i-jaundice ekati lami?
Ngo- ukuhlolwa kwelabhoratri nokuxilonga zibalulekile, kanye nomlando ogcwele wemitholampilo udokotela wezilwane azowulungiselela ngokususelwa kulwazi esilunikezayo. Noma kungabonakala kungabalulekile, kufanele sixhumane yonke imininingwane ngokuningiliziwe.
Ukwenza ukubalwa kwegazi kanye ne-serum biochemistry, kanye nokunquma i-hematocrit kanye namaprotheni esewonke, kungukuqala kochungechunge lwezivivinyo ezihambisanayo.
Kumakati ane-jaundice, kujwayelekile ukuthola ifayela le- ama-enzyme wesibindi aphakeme, kodwa lokhu akubonisi ukuthi imbangela isifo esiyisisekelo noma sesibili se-hepatobiliary. Kwesinye isikhathi, ukwanda ngokweqile kwesinye sazo maqondana nezinye kungasihola, kepha kufanele kwenziwe ucwaningo lwe-ultrasound kanye nemisebe (singabona izixuku, izithiyo ze-duodenal, ukungena kwamafutha ...). Ngaphambi kwakho konke lokhu, umlando womtholampilo nokuhlolwa komzimba bangavumela udokotela wezilwane ukuthi athole amaqhubu e-thyroid, uketshezi esiswini (ascites) futhi abone nokuvezwa okungenzeka yimithi ye-hepatotoxic.
Kumele sibheke i-jaundice njengesibonakaliso somtholampilo esabiwe yizinguquko eziningi zazo zonke izinhlobo, yingakho kubalulekile ukuthola umsuka wayo ngomlando ophelele, ukuhlolwa ngokomzimba kanye nezivivinyo zelabhorethri nezokuxilonga.
Lo mbhalo wenzelwe imininingwane kuphela, kwaPeritoAnimal.com.br asikwazi ukunquma ukwelashwa kwezilwane noma ukwenza noma yiluphi uhlobo lokuxilongwa. Siphakamisa ukuthi uthathe isilwane sakho uye kudokotela wezilwane uma kungenzeka ukuthi unanoma yiluphi uhlobo lwesimo noma ukungaphatheki kahle.