-Delile
- Yini iCushing Syndrome?
- I-Cushing syndrome ezinjeni: izimbangela
- Izimpawu ze-Cushing syndrome
- I-Cushing syndrome: ukubekwa phambili kwezinye izinja
- I-Cushing syndrome: umsuka ku-pituitary:
- I-Cushing syndrome: umsuka kwizindlala ze-adrenal:
- I-Cushing syndrome: imvelaphi ye-iatrogenic ngenxa yokuphathwa okuphikisanayo noma ngokweqile kwama-glucocorticoids neminye imithi:
- I-Cushing syndrome: ukuxilongwa nokwelashwa
Izinja zabelane ngempilo yazo nathi izinkulungwane zeminyaka. Siyanda siba nabangane abanoboya emakhaya ethu, noma ngisho nangaphezu koyedwa, esifuna ukwabelana naye konke. Kodwa-ke, sidinga ukungaguquguquki futhi siqaphele umthwalo wemfanelo ohambisana nokuphathelene nesilwane, njengesidalwa esiphilayo, esinamalungelo aso. Akufanele sigcine ngokumgona nje kuphela kepha sibuye sihlangabezane nazo zonke izidingo zakhe zomzimba nezengqondo, imidlwane kanye nabantu abadala kanye nabantu abadala.
Impela, uma ungumngane ojabulayo futhi obhekele inja yakho, usuvele waziswa ngezifo ezivame kakhulu zezinja. Kule ndatshana entsha yePeritoAnimal, sizoletha imininingwane mayelana ne- ICushing's Syndrome ezinjeni - Izimpawu Nezimbangela, ngaphezu kokunikeza imininingwane ehlobene kakhulu. Funda kabanzi ukuze ufunde ukuthi lesi sifo sibathinta kanjani abangane bethu abanoboya nokuthi benzeni ngakho.
Yini iCushing Syndrome?
ICushing's syndrome yaziwa nangokuthi yi-hyperadrenocorticism, futhi iyi- isifo se-endocrine (hormonal), okwenzeka lapho umzimba ukhiqiza amazinga aphezulu we-hormone cortisol ngokungapheli. ICortisol ikhiqizwa kwizindlala ze-adrenal, eziseduze nezinso.
Izinga elanele le-cortisol liyasisiza ukuze imizimba yethu iphendule ngendlela ejwayelekile ekucindezelekeni, isize ukulinganisa isisindo somzimba, ukuba nezicubu ezinhle nokwakheka kwesikhumba, njll. Ngakolunye uhlangothi, lapho umzimba uhlangabezana nokwanda kwe-cortisol futhi kunokukhiqizwa ngokweqile kwaleli hormone, amasosha omzimba abe buthakathaka, futhi umzimba uchayeka ezifweni nasezifweni ezingahle zibe khona, njengesifo sikashukela. Le hormone ngokweqile ingalimaza nezitho eziningi ezahlukahlukene, kunciphisa kakhulu ubungqabavu kanye nekhwalithi yempilo yesilwane esinalesi sifo.
Ngaphezu kwalokho, izimpawu zidideka kalula nalabo okubangelwa ukuguga okuvamile. Kungakho imidlwane eminingi ingatholakali ukuthi ine-cushing syndrome, njengoba izimpawu zinganakwa abanye babaqaphi bemidlwane endala. Kubalulekile ukuthola izimpawu ngokushesha okukhulu futhi wenze konke ukuhlolwa okungenzeka kuze kube yilapho kutholakala umsuka we-cushing syndrome futhi welashwa ngokushesha okukhulu.
I-Cushing syndrome ezinjeni: izimbangela
Kunemvelaphi engaphezu kweyodwa noma imbangela ye-cushing syndrome ezinjeni. Ngokuqondile, zintathu izimbangela ezingadala ukwanda ngokweqile kwe-cortisol:
- Ukungasebenzi kahle kwendlala yesikhumba noma ye-pituitary;
- Ukungasebenzi kahle kwezindlala ze-adrenal noma ze-adrenal;
- Umsuka we-Iatrogenic, owenzeka okwesibili ngenxa yokwelashwa ngama-glucocorticoids, ama-corticosteroids kanye nezidakamizwa ezine-progesterone kanye nezinye, ukuphatha izifo ezithile ezinjeni.
Njengoba sesishilo, izindlala ze-adrenal zikhiqiza i-hormone cortisol, ngakho-ke inkinga kulezi zindlala ingadala i-cushing syndrome. Kodwa-ke, izindlala ze-adrenal nazo zilawulwa yi-hormone efihliwe yi-pituitary noma i-pituitary gland, etholakala ebuchosheni. Ngakho-ke, inkinga ku-pituitary nayo ingadala ukuthi amazinga e-cortisol aphelelwe ukulawula. Ekugcineni, kukhona ama-glucocorticoids neminye imithi esetshenziselwa ukwelapha izifo ezithile ezinjeni, kepha uma isetshenziswe kabi, ngokwesibonelo emazweni aphikisiwe noma ngamanani aphezulu kakhulu nezikhathi, angagcina ekhiqize i-cushing syndrome, njengoba iguqula ukukhiqizwa kwe-cortisol.
Kungashiwo ukuthi umsuka ovame kakhulu we-cushing syndrome, noma i-hyperadrenocorticism, phakathi Ama-80-85% wamacala imvamisa kuyisimila noma i-hypertrophy ku-pituitary, egcina inani eliphakeme lehomoni ye-ACTH, enesibopho sokwenza ama-adrenali akhiqize i-cortisol eningi kunokujwayelekile. Enye indlela engajwayelekile, phakathi I-15-20% yamacala avela kwizindlala ze-adrenal, imvamisa ngenxa yesimila noma i-hyperplasia. Imvelaphi ye-Iatrogenic incane kakhulu.
Kubaluleke kakhulu ukuthi imbangela ye-cushing syndrome ezinjeni itholwe ngokushesha okukhulu. Vele, udokotela wezilwane onguchwepheshe kufanele akwenze lokhu ngokwenza izivivinyo eziningana futhi anikeze ukwelashwa okufanelekile kakhulu okuzoxhomeka ngokuphelele kusizathu noma umsuka we-cushing syndrome ezinjeni.
Izimpawu ze-Cushing syndrome
Izimpawu eziningi ezibonakalayo zingadidaniswa nezimpawu zokuguga ezijwayelekile ezinjeni. futhi ngenxa yalokhu, abantu abaningi abaqapheli ukuthi izimpawu nezimpawu ezivezwa ngumngani wabo othembekile kungenxa yokungajwayelekile ekukhiqizeni i-cortisol, noma i-Cushing's syndrome. Njengoba lesi sifo sivame ukukhula kancane, izimpawu zivela kancane kancane, futhi kungathatha izinyanga noma ngisho neminyaka ukuthi zonke zivele. Khumbula ukuthi akuzona zonke izinja eziphendula ngendlela efanayo ekwandiseni i-cortisol, ngakho-ke kungenzeka ukuthi akuzona zonke izinja ezibonisa izimpawu ezifanayo.
Yize bekhona abanye, i- izimpawu mizimpawu ezivame kakhulu ze-cushing syndrome zimi kanje:
- Ukwanda ukoma nokuchama
- Ukwanda kwesifiso
- Izinkinga zesikhumba nezifo
- I-Alopecia
- Isikhumba hyperpigmentation
- ikhwalithi yezinwele empofu
- Ukuhefuzela njalo;
- ubuthakathaka bemisipha kanye ne-atrophy
- Imikhuba emibi
- Ukukhuluphala okutholakala esiswini (isisu esivuvukile)
- Ukukhulisa usayizi wesibindi
- izifo eziphindaphindayo zesikhumba
- Ezimweni ezithuthukile zemvelaphi yamapayipi, izinguquko zemizwa zenzeka
- Izinguquko kumjikelezo wokuzala wabesifazane
- I-atrophy yobufakazi emadodeni
Kwesinye isikhathi, indlela eqonde kakhulu yokubona ukuthi i-cushing syndrome akuyona izimpawu, kepha lapho udokotela wezilwane ethola isifo sesibili esivezwa yilesi sifo, njengesifo sikashukela, i-hypothyroidism yesibili, izinguquko zezinzwa nokuziphatha, phakathi kwamanye amathuba.
I-Cushing syndrome: ukubekwa phambili kwezinye izinja
Lokhu okungajwayelekile ekusebenzeni kwezindlala ze-adrenal ezibangela ukukhiqizwa ngokweqile kwe-cortisol kuvame kakhulu ezinjeni ezindala kunezincane, imvamisa ivela eminyakeni eyisithupha futhi ikakhulukazi emidlwane engaphezu kweminyaka eyishumi. Kungathinta nezinja ezihlangabezana neziqephu zokucindezeleka ezivela kolunye uhlobo lwenkinga noma ezinye izimo ezihlobene. Kubukeka kunobufakazi bokucabanga ukuthi amacala avame kakhulu we-Cushing's syndrome avela e-pituitary avela ezinjeni ezinesisindo esingaphansi kwama-20 kg, kanti amacala emvelaphi ye-adrenal atholakala kaningi ezinjeni ezinesisindo esingaphezu kwama-20 kg, yize uhlobo lwe-adrenal nalo luvela ngemidlwane emincane.
Yize ucansi lwenja lungakuthinti ukuvela kwalesi sifo se-hormonal, lolu hlobo lubukeka lunethonya elithile. Lezi izi ezinye izinhlobo ezivame ukuhlushwa yi-cushing syndrome, ngokusho komthombo wenkinga:
I-Cushing syndrome: umsuka ku-pituitary:
- Daschshund;
- Poodle;
- I-Boston terriers;
- ISchnauzer encane;
- IMalta Bichon;
- UBobtail.
I-Cushing syndrome: umsuka kwizindlala ze-adrenal:
- Indawo yaseYorkshire;
- Dachshund;
- I-Poodle encane;
- Umalusi waseJalimane.
I-Cushing syndrome: imvelaphi ye-iatrogenic ngenxa yokuphathwa okuphikisanayo noma ngokweqile kwama-glucocorticoids neminye imithi:
- Isibhakela;
- Umfundisi wasePyrenees;
- ILabrador retriever;
- Poodle.
I-Cushing syndrome: ukuxilongwa nokwelashwa
Kubaluleke kakhulu ukuthi uma sithola noma yiziphi izimpawu okuxoxwe ngazo esigabeni esedlule, noma ngabe zingabonakala njengokuguga, siye udokotela wezilwane othembekile ukwenza noma yiziphi izivivinyo abona zidingeka ukukhipha noma ukuxilonga i-cushing syndrome ezinweleni zethu futhi sikhombise ikhambi nokwelashwa okungcono kakhulu.
Udokotela wezilwane kufanele yenza izivivinyo eziningana, njengokuhlolwa kwegazi, ukuhlolwa komchamo, ama-biopsies esikhumba ezindaweni ezibonisa ushintsho, ama-X-ray, ama-ultrasound, izivivinyo ezithile ukukala ukuminyana kwe-cortisol egazini futhi, uma usola ukuthi ivela kuphi ku-pituitary, kufanele futhi wenze i-CT kanye neMRI.
Udokotela wezilwane kufanele anikeze ukwelashwa okufanele kakhulu kwe-cushing syndrome, okuzoncika ngokupheleleimvelaphi i-syndrome ezoba nayo kuzo zonke izinja. Ukwelashwa kungaba ukwelashwa kwemithi impilo yonke noma kuze kube yilapho inja ingahlinzwa ukuze kulawulwe amazinga e-cortisol. Ukwelashwa kungabuye kuhlinzwe ngqo ukuze kususwe isimila noma kuxazululwe inkinga evezwe kwizindlala, kungaba kwi-adrenal noma i-pituitary. Ukwelashwa okususelwa ekhemotherapy noma ekwelashweni ngemisebe nakho kungabhekwa uma izicubu zingasebenzi. Ngakolunye uhlangothi, uma imbangela yesifo ingemvelaphi ye-iatrogenic, kwanele ukumisa umuthi wolunye ukwelashwa okwenziwayo futhi obangela i-cushing syndrome.
Kuyadingeka ukuthi ubheke eminye imingcele eminingi yempilo yenja namathuba esimweni ngasinye ukunquma ukuthi kungcono yini ukulandela ukwelashwa noma okunye. Futhi, kuzofanele sikwenze yenza ukuvakashelwa ngezikhathi ezithile kudokotela wezilwane ukulawula amazinga we-cortisol futhi ulungise imithi uma kunesidingo, kanye nokulawula inqubo yokusebenza ngemuva.
Lo mbhalo wenzelwe imininingwane kuphela, kwaPeritoAnimal.com.br asikwazi ukunquma ukwelashwa kwezilwane noma ukwenza noma yiluphi uhlobo lokuxilongwa. Siphakamisa ukuthi uthathe isilwane sakho uye kudokotela wezilwane uma kungenzeka ukuthi unanoma yiluphi uhlobo lwesimo noma ukungaphatheki kahle.